Description
Melanotan-2 (MT-2) is a synthetic cyclic heptapeptide analogue of alpha-Melanocyte Stimulating Hormone (α-MSH). Unlike its linear counterpart MT-1, MT-2 possesses a lactam bridge structure. This cyclization significantly increases its resistance to enzymatic degradation, resulting in greater stability and a prolonged half-life in experimental environments.
Mechanism of Action
MT-2 is characterized by its high potency and broad binding profile across the melanocortin receptor family. It acts as a non-selective agonist with significant affinity for MC1R, MC3R, MC4R, and MC5R.
This broad receptor activity makes MT-2 a critical tool for researchers investigating the complex interplay of the melanocortin system, moving beyond simple melanogenesis to explore central nervous system (CNS) signaling and peripheral physiological responses.
Technical Specifications:
Structure: Cyclic lactam heptapeptide.
Purity: ≥98% (determined by HPLC).
Format: Sterile, lyophilized powder for maximum stability.
Storage: Store desiccated at -20°C away from light.
Statement of Use: This product is intended solely for laboratory research and in vitro applications. It is NOT for human consumption, diagnostic, or therapeutic use.





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