Semax is a synthetic heptapeptide, specifically an analog of a fragment of the adrenocorticotropic hormone (ACTH 4-10). It is primarily categorized in research as a neuroprotective and nootropic agent.
Core Description

Molecular Structure: It consists of a specific amino acid sequence (Met-Glu-His-Phe-Pro-Gly-Pro). The addition of the “Pro-Gly-Pro” tail is a key structural feature that increases its stability and resistance to enzymatic breakdown in the body.

Primary Function: In laboratory settings, it is studied for its ability to increase levels of Brain-Derived Neurotrophic Factor (BDNF) and Nerve Growth Factor (NGF). These proteins are essential for the survival, growth, and maintenance of neurons.

Research Intent: Researchers typically utilize Semax to explore its effects on memory enhancement, learning, mental stamina, and recovery from neurological injuries such as stroke or hypoxia.

Product Specifications

Format: It is most commonly supplied as a lyophilized (freeze-dried) powder in a 10mg vial. This format preserves the integrity of the peptide until it is ready for reconstitution.

Purity: High-quality research-grade Semax typically maintains a purity level of \geq\99%, verified via High-Performance Liquid Chromatography (HPLC) Union Biolabs.

Storage:

Lyophilized (Dry): Best stored in a freezer (−20∘C−20∘C) to maintain long-term stability.

Reconstituted (Liquid): Must be kept refrigerated ($2\text{–}8 ^\circ \text{C}$) and protected from light; it should generally be used within 30 days of mixing Dosage Peptide.

Common Research Applications

Cognitive Enhancement: Studied for its potential to improve focus and mental clarity without the “jittery” effects associated with traditional stimulants.

Neuroprotection: Investigated for its ability to protect the brain against oxidative stress and inflammatory damage.

Mood Regulation: Early research suggests it may modulate neurotransmitters like dopamine and serotonin, potentially influencing mood and stress resilience.

Standard Reconstitution (Educational Reference)

In a research environment, a 10mg vial is often reconstituted with 3.0 mL of bacteriostatic water.

This creates a concentration of approximately 3.33 mg/mL.

In this dilution, a standard dose of 500 mcg would equal 15 units on a U-100 insulin syringe Dosage Peptide.

Important Note: Semax is approved for medical use only in Russia. In the US, UK, and EU, it is not FDA or EMA approved and is strictly intended for laboratory research and educational purposes only. It is not for human or animal consumption.